ClematichineNOSide AR 是从中药威灵仙中提取的一种天然产物,具有抗炎和免疫抑制特性,对 PI3K/Akt 信号通路和与胶原诱导的关节炎相关的 TNF-α± 具有抗关节炎作用。
产品描述
Clematichinenoside AR exerts anti-inflammatory and immunosuppressive properties, it has anti-arthritic effects on PI3K/Akt signaling pathway and TNF-α± associated with collagen-induced arthritis.
体外活性
C-AR was incubated with the content of the large intestine. The culture solution was collected at different time points and analyzed for the metabolites of C-AR. Eight metabolites were identified by liquid chromatography/quadrupole time-of-flight mass spectrometry. M1, M2 and M5 were the major metabolites. In addition, it was proposed that deglycosylation was the only pathway contributing to the biotransformation of C-AR in rat intestinal microflora.
Cas No.
761425-93-8
分子式
C82H134O43
分子量
1807.92
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years