Escin IA;Aescin IA是从马蹄中七叶树分离出的一种三萜皂苷,抑制HIV-1蛋白酶,IC50值为 35 μM。它具有抗 TNBC 转移活性,其作用机制涉及通过下调 LOXL2 表达抑制上皮-间质转化过程。
产品描述
Escin IA is a triterpene saponin isolated from horse chestnut, which inhibits HIV-1 protease with IC50 values of 35 μM. Escin IA has anti-TNBC metastasis activity, and its action mechanisms involved inhibition of epithelial-mesenchymal transition process by down-regulating LOXL2 expression[1][2].
Cas No.
123748-68-5
分子式
C55H86O24
分子量
1131.269
别名
Escin IA;Aescin IA;七叶皂苷A;七叶皂苷 A
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years