产品描述
7-O-Methylaloeresin A shows significant antioxidant activity, it also has moderate inhibitory active on BACE.
体外活性
The latex and its two constituents were assessed for their possible antimicrobial activities against 23 bacterial and four fungal strains using the disc diffusion method and their antioxidant activity by two complementary test systems, namely 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2-deoxyribose degradation assay methods. The isolated compounds showed promising results against various pathogenic bacterial and fungal strains in comparison with standard drugs. Moreover, 7-O-Methylaloeresin A exhibited good activity against multiple drug resistant Staphylococcus aureus (NCTC 11994) and Salmonella typhimurium (ATCC 1255) with MIC values of 0.72 and 0.18 mm, respectively. Among the fungal strains tested, Candida albicans (ATCC 10231) was the most susceptible organism to the latex and the two isolated compounds. The latex and isolated compounds also showed significant activities on both antioxidant assays with the highest activity being observed for 7-O-Methylaloeresin A, which gave IC(50) values of 0.026 mm and 0.021 mm for DPPH and 2-deoxyribose degradation assay, respectively.
Cas No.
329361-25-3
分子式
C29H30O11
分子量
554.54
别名
7-O-甲基片木素A;7-O-甲基芦荟新甙A
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years