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Neoisoastilbin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Neoisoastilbin图片
CAS NO:54141-72-9
包装与价格:
包装价格(元)
10 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍
Neoisoastilbin 具有抗炎、抗氧化、抗尿酸过多等生物特性。

产品描述

Neoisoastilbin may have antioxidant and anti-inflammatory activities.

体外活性

Phenolic-enriched extract of S. glabra (PEESG) was extracted with 70% ethanol and purified by HP-20 column chromatography. Its antioxidant and anti-inflammatory activities were evaluated by radical scavenging assay, reducing power determination, and lipopolysaccharide (LPS)-induced RAW264.7 cells assays, respectively. PEESG exhibited obviously scavenging capacity for DPPH and ABTS radicals, as well as significant reducing power for ferric ion. Particularly, PEESG (12.5-50 μg/mL) showed a significantly higher efficiency for scavenging ABTS than that of ascorbic acid and no significant difference with ascorbic acid for DPPH scavenging. PEESG also possessed a significant suppression effect on proinflammatory mediators production, such as nitric oxide (NO), tumor necrosis factor-α± (TNF-α±), and interleukin-6 (IL-6), in LPS-induced RAW264.7 cells. In addition, the main ingredients of PEESG were identified using ultrahigh pressure liquid chromatography coupled to electrospray mass spectrometry (U-HPLC-ESI-MS). Seventeen components, including 5-O-caffeoylshikimic acid, neoastilbin, astilbin, Neoisoastilbin, isoastilbin, engetin and isoengeletin were identified.

Cas No.

54141-72-9

分子式

C21H22O11

分子量

450.4

储存和溶解度

DMSO:55 mg/ml (122.11 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years