Norwogonin 是从黄芩中分离出来的,对肠道病毒 71 具有抗病毒活性,IC50为 31.83 μg/ ml。
产品描述
Norwogonin, isolated from Scutellaria baicalensis Georgi, possesses antiviral activity against Enterovirus 71 (IC50: 31.83 μg/ml).
体外活性
Norwogonin (0.4, 2, 10, and 50 μg/mL; 48 hours) inhibits Enterovirus 71 (EV71) replication in Vero cells and prevents the cytotoxicity induced by EV71 infection. Norwogonin (50 μg/mL; 48 hours) dramatically decreases viral VP2 protein expression and strongly decreases the expression of the EV71 NCR gene at 48 h.
Cas No.
4443-09-8
分子式
C15H10O5
分子量
270.24
别名
5,7,8-Trihydroxyflavone;去甲汉黄芩素
储存和溶解度
DMSO:20mg/ml(74.01mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years