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Baicalin methyl ester
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Baicalin methyl ester图片
CAS NO:82475-03-4
包装与价格:
包装价格(元)
10 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍
Baicalin methyl ester 是黄芩苷根的一种成分。

产品描述

Baicalin methyl ester shows inhibitory effects on the Avian Myeloblastosis Virus reverse transcriptase (AMV-RT).

体外活性

One hundred-ninety flavonoids and 75 alkaloids were studied for their inhibitory effects on the Avian Myeloblastosis Virus reverse transcriptase (AMV-RT) by using (rA) n-p(dT)<12-18>or (rC) n-p(dG)<12-18>as a template-primer. Of the flavonoids tested, 6-hydroxyluteolin (50), pedalitin (52), 6-hydroxykaempferol (109) and quercetagetin (129), were the most potent inhibitors with IC50?:10 μM. Five other flavonoids, baicalein (19), Baicalin methyl ester (23), scutellarein (33), myricetin (126) and gossypetin (130), gave IC50 between 35 and 200 μM. The kinetic studies on 50, 126 and 130 gave the inhibitory constants ki of 10, 94 and 90 μM, respectively, with respect to the substrate and 5, 200 and 100 μM, respectively, with respect to the template-primer. Structurally different alkaloids such as isoquinoline, indol, steroidal, quinolizidine, pyrrolizidine, pyridine and imidazole alkaloids were also investigated for the activity and berberine type alkaloids were shown to have a strong inhibitory activity.

Cas No.

82475-03-4

分子式

C22H20O11

分子量

460.39

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years