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Rosmanol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Rosmanol图片
CAS NO:80225-53-2
包装与价格:
包装价格(元)
20 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍
ROSmanol 能够显著抑制脂多糖诱导的 INOS、COX-2 的表达,抑制低密度脂蛋白的氧化,并具有抗炎作用。

产品描述

Rosmanol has antioxidant activity, it can activate the antioxidant response element. Rosmanol has biphasic modulation of GABAA receptors, demonstrates CNS activity in mouse models of antinociception, antidepressant and anxiolysis. Rosmanol potently induces apoptosis through both the mitochondrial apoptotic pathway and death receptor pathway in human colon adenocarcinoma COLO 205 cells. Rosmanol has anti-inflammatory activity, it potently inhibits lipopolysaccharide-induced iNOS and COX-2 expression through downregulating MAPK, NF-kappaB, STAT3 and C/EBP signaling pathways.

Cas No.

80225-53-2

分子式

C20H26O5

分子量

346.423

储存和溶解度

Chloroform:Soluble
DMSO:60 mg/ml (173.2 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years