产品描述
Prunasin is a kind of enzyme inhibitors.
体外活性
As shown by high pressure liquid chromatography, Prunasin is transferred essentially intact across the intestinal wall, without cleavage of the glycosidic bond and thus no formation of benzaldehyde or cyanide during the mucosal passage. 3. Only the jejunal transfer of Prunasin followed saturation kinetics (vmax = 1.6 mumol cm-1 min-1; KT = 460 mumol l-1) and exhibited a clearsodium-ion dependence. As indicated by the temperature dependence, only the jejunal mucosa-to-serosa transfer and the corresponding tissue uptake of Prunasin required apparently high activation energies. Transfer in the terminal ileum showed diffusion characteristics. 4. Jejunal methyl alpha-D-glucoside transfer was inhibited by the presence of Prunasin. Furthermore, the tissue uptake of methyl alpha-D-glucoside in rat jejunum was competitively inhibited by Prunasin.
Cas No.
99-18-3
分子式
C14H17NO6
分子量
295.29
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years