Cichoriin 对SARS-CoV-2有明显活性，是治疗重症COVID-19的潜在候选物质。

Cichoriin is a photosensitive compound, it could be used as herbal photosensitizing agent in treating benign breast tumor in rats.

METHODS AND RESULTS:Four flavonoids including kaempferol (1), isoscutellarin (2), umbelliferone (3) and Cichoriin (4) have been isolated from Streptomyces sp. Tc052, an endophyte in the root tissue of Alpinia galanga Swartz. The evaluation for protective effect of compounds 1-4 against glutamate-induced cytotoxicity in hippocampal HT22 cell line was conducted, Compounds 1 and 2 showed significant effective protection ratios of 62.4+2.8 and 55.3+3.4%, respectively, at a concentration of 100 μM, whereas compounds 3-4 were inactive. Compounds 1 and 2 showed potent scavenging effects on DPPH radical exhibiting IC50 value of 60.74 and 75.65 μM, respectively. CONCLUSIONS: These results suggest that compounds 1 and 2 may possess the neuroprotective activity against oxdative cellular injuries.

531-58-8

C15H16O9

340.28

DMSO:60 mg/ml (176.33 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years