您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Silymarin
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Silymarin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Silymarin图片
CAS NO:65666-07-1
包装与价格:
包装价格(元)
50 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
水飞蓟素
Silybin B
产品介绍
Silymarin 是一种多酚类黄酮,是从水飞蓟或水飞蓟的种子中提取的一种 SARS-CoV-2 主蛋白酶抑制剂。它可降低肿瘤细胞的增殖,血管生成以及胰岛素抵抗,用于预防和治疗肝脏疾病,有潜力研究 COVID-19 。

产品描述

Silymarin (Silybin B) is a polyphenolic flavonoid that extracts from the milk thistle or seeds of Silybum marianum. It is used in the prevention and treatment of liver diseases.

体外活性

Mechanism of Silymarin involves different biochemical reactions, such as stimulation of the rate of ribosomal RNA synthesis by stimulating the transcription of polymerase I and ribosomal RNA genes, blockage of alpha-glycoside loops toxin intake, and protection of cell membranes from free radical-induced damage. Silymarin also displays a substantial protective effect against UVB-induced canceration at different stages, possibly through its strong antioxidant properties.

体内活性

The intravenous injection LD50 of Silymarin is 391.4 mg/kg, 70.1 mg/kg, 142.3 mg/kg for mice, rats, rabbits, respectively.

Cas No.

65666-07-1

分子式

C25H22O10

分子量

482.441

别名

水飞蓟素;Silybin B

储存和溶解度

H2O:<1 mgml
DMSO:97 mg/mL (201.06 mM)
Ethanol:1 mg/mL (2.07 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years