Persicogenin 是分离自Rhus retinorRhoea中,具有抗癌作用。
产品描述
Persicogenin has anticancer, antimutagenic, and antileishmanial activities, it can inhibit the proliferation of mouse tsFT210 cancer cells, it mainly inhibits cell cycle at the G2/M phase in a dose-dependent manner.
体外活性
Compound 1 exhibited moderate antimycobacterial activity against Mycobacterium tuberculosis with the MIC value of 174.8 microM, whereas compounds 4, 7, and 8 exhibited weak activity with the MIC values of 606.0, 704.2 and 699.3 microM respectively. Compound 7 showed moderate cytotoxicity against human small cell lung cancer (NCI-H187) cells with the MIC value of 24.6 microM, whereas compound 8 exhibited moderate toxicity against NCI-H187 cells and week toxicity against human breast cancer (BC) cells with the MIC values of 19.2 and 38.4 microM respectively[1]
Cas No.
28590-40-1
分子式
C17H16O6
分子量
316.31
储存和溶解度
DMSO:60 mg/ml (189.69 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years