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DHODH-IN-3
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:1148126-04-8
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

DHODH-IN-3 (compound 3) is a highly potent inhibitor of Human Dihydroorotate Dehydrogenases (HsDHODH) with an IC50 value of 261 nM. DHODH-IN-3 binds to the the ubiquinone binding cavities in DHODH with a Kiapp of 32 nM. DHODH-IN-3 has the highly potential for malaria treatment. References: [1]. Davies M, et al. Structure-based design, synthesis, and characterization of inhibitors of human and Plasmodium falciparum dihydroorotate dehydrogenases.J Med Chem. 2009 May 14;52(9):2683-93.

纯度:≥98%

CAS:1148126-04-8