LY88074 (Compound 88074) is a Raloxifene analog lacking the basic side chain. Raloxifene is a specific estrogen receptor modulator, and reduces fracture risk at least in part by improving the mechanical properties of bone in a cell- and estrogen receptor-independent manner. References: [1]. Bivi N, et al. Structural features underlying raloxifene's biophysical interaction with bone matrix. Bioorg Med Chem. 2016 Feb 15;24(4):759-67.
纯度:≥98%
CAS:177744-96-6