Gentisin 是一种提取于 Gentianae radix (Gentianaceae) 的天然化合物,具有诱变活性。
产品描述
Gentisin is a novel inhibitor of vascular smooth muscle cells (VSMC) proliferation with an IC50 value of 7.84 μM. Gentisin has mutagenic activity.
体外活性
The anti-proliferative effect of Gentisin was confirmed by the quantification of DNA synthesis (BrdU incorporation) in VSMC. Cell death quantification (determined by LDH release in the culture medium) revealed that Gentisin was not cytotoxic in the investigated concentration range[1].
Cas No.
437-50-3
分子式
C14H10O5
分子量
258.23
别名
龍膽根素;龙胆根素
储存和溶解度
DMSO:80 mg/mL (309.80 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years