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Nardosinone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Nardosinone图片
CAS NO:23720-80-1
包装与价格:
包装价格(元)
20 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
苷松新酮
甘松新酮
产品介绍
Nardosinone 是的一个dbcAMP和stauROSporine的神经生成作用增强剂,分离自Nardostachys chinensis中。它可能成为一种有用的药理学工具,不仅可用于研究神经生长因子 (NGF) 的作用机理,而且可用于研究神经毒性物质的作用机理。

产品描述

1. Nardosinone has inhibitory effect on Ang II-induced hypertrophy in H9c2 cells, might be mediated by targeting PI3K/Akt and MEK/ERK signaling pathways. 2. Nardosinone could protect against the neuronal injury exposed to OGD, which may be relevant to the promotion of PKA and ERK signaling pathway. 3. Nardosinone enhances staurosporine- or dbcAMP-induced neurite outgrowth from PC12D cells, probably by amplifying both the MAP kinase-dependent and -independent signaling pathways of dbcAMP and staurosporine. 4. The enhancement of NGF-induced neurite outgrowth from PC12D cells by Nardosinone involves activation of a down-stream step of the MAP kinase-dependent cascade of NGF coupled with PKC.

Cas No.

23720-80-1

分子式

C15H22O3

分子量

250.338

别名

苷松新酮;甘松新酮

储存和溶解度

Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble
DMSO:46 mg/mL(183.8 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years