Ellipticine 是一种有效的抗肿瘤剂,抑制DNA拓扑异构酶II活性,对白血病、神经母细胞瘤和胶质母细胞瘤有部分活性。
产品描述
Ellipticine is a potent antineoplastic agent exhibiting multiple mechanisms of action, IC50 of 0.67±0.06, 1.25±0.13, 1.25±0.13, 0.67±0.06, 0.27±0.02, 0.49±0.04, 0.44±0.03, and 1.48±0.62 μM for Leukemia HL-60, Breast adenocarcinoma MCF-7, Breast adenocarcinoma MCF-7, Leukemia HL-60, Neuroblastoma IMR-32, Neuroblastoma UKF-NB-4, Neuroblastoma UKF-NB-3, and Glioblastoma U87 mg cell, respectively.
Cas No.
519-23-3
分子式
C17H14N2
分子量
246.313
别名
Elliptisine;玫瑰树碱;NSC 71795
储存和溶解度
DMSO:5.8 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years