BRD32048 可以与与ETV1直接结合,KD为 17.1 μM。BRD32048调节 ETV1 介导的转录活性和 ETV1 驱动的癌细胞侵袭。 BRD32048可以抑制ETV1 乙酰化并促进其降解。
产品描述
BRD32048 is a top candidate ETV1 perturbagen. BRD32048 inhibits p300-dependent acetylation of ETV1, thereby promoting its degradation.
Cas No.
433694-46-3
分子式
C16H22N6O
分子量
314.39
别名
BRD 32048;BRD-32048
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years