UF010 是一种有效的选择性 HADC 抑制剂，对 HDAC 1、2、3 和 8 的 IC50 分别为 0.5 μM、0.1 μM、0.06 μM 和 1.5 μM。它比作用于其他HDACs选择性高6倍多。

UF010 is a potent and selective HADC inhibitor with IC50 ~0.06 μM, 0.1 μM, 0.5 μM and 1.5 μM for HDACs 3, 2, 1 and 8, respectively.

The combination of paritaprevir, ritonavir, ombitasvir (an NS5A protein inhibitor), and dasabuvir (an NS5B non-nucleoside polymerase inhibitor) with or without RBV has been approved to treat HCV genotype 1 infections1[1].

537672-41-6

C11H15BrN2O

271.158

DMSO:27.1 mg/mL(100 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years