Bufexamac 是 HDAC6 和 HDAC10 的抑制剂，也是一种COX抑制剂，用于释放 IFN-α，具有抗炎、镇痛和解热作用。

Bufexamac is a COX inhibitor for IFN-α release with anti-inflammatory, analgesic, and antipyretic action.

Bufexamac is a specific inhibitor of class IIB histone deacetylases (HDAC6 and HDAC10). Treatment of peripheral blood mononuclear cells with bufexamac inhibits the secretion of IFN-α. [1] Bufexamac is a frequent and relevant contact sensitizer. Bufexamac is a non-steroidal anti-inflammatory drug. [2]

2438-72-4

C12H17NO3

223.27

Bufexamic acid;丁苯羟酸

DMSO:42 mg/mL (188.1 mM)
Ethanol:3 mg/mL (13.43 mM)
H2O:<1 mgml
Powder: -20°C for 3 years
In solvent: -80°C for 2 years