Ganciclovir sodium 是核苷类似物和口服抗病毒药物，具有抗病毒活性，尤其是针对巨细胞病毒和单纯疱疹病毒 1 型。

Ganciclovir Sodium is the sodium salt of Ganciclovir with antiviral activity, especially against cytomegalovirus (CMV) and herpes simplex virus type 1 (HSV-1).

Ganciclovir showed activity against feline herpesvirus type-1 (FHV-1, IC50 = 5.2 microM)[1].

In adult rats, the intracochlear diffusion of ganciclovir was shown to achieve the same concentration as in blood. In gestating mice, transplacental diffusion was observed, with a fetal-to-maternal blood ratio of 0.5. In newborn mice, the plasma concentration profile of ganciclovir showed a peak at 2 h followed by a gradual decrease. In adult mice, the concentration peaked at 1 h, but became undetectable by 2 h after injection. Counts of white blood cells, red blood cells and platelets decreased significantly in ganciclovir-treated newborn mice[3].

107910-75-8

C9H13N5NaO4

278.22

2'-Nor-2'-deoxyguanosine sodium;更昔洛韦钠;BW 759 sodium;RS-21592 sodium;Cytovene IV sodium

DMSO:4 mg/mL (14.43 mM)
H2O:40 mg/mL (144.29 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years