Imiquimod 是一种免疫反应修饰剂,可作为 toll 样受体7 激动剂。它有抗病毒和抗肿瘤作用,可研究外生殖器、肛周疣、癌症和 COVID-19。
产品描述
Imiquimod is an immune response modifier that acts as a toll-like receptor 7 agonist.
体内活性
In animal models, imiquimod stimulates the innate immune response by increasing NK cell activity, activating macrophages to secrete cytokines and nitric oxide, and inducing proliferation and differentiation of B lymphocytes. Imiquimod stimulates the innate immune response through induction, synthesis, and release of cytokines, including interferon-a (IFN-α), interleukin (IL)-6, and tumour necrosis factor (TNF)-α[1].
Cas No.
99011-02-6
分子式
C14H16N4
分子量
240.31
别名
咪喹莫特;S-26308;R 837
储存和溶解度
H2O:Insoluble
DMSO:2.4 mg/ml (10 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years