CU-CPT-8m 是TLR8特异性拮抗剂，IC50值为 67 nM。

CU-CPT-8m is an toll-like receptor 8 (TLR8) antagonist (IC50 : 67 nM)

CU-CPT8m decreases TNF-α and IL-8 levels in synovial cells derived from patients with osteoarthritis and TNF-α levels in PBMCs derived from patients with rheumatoid arthritis.

125079-83-6

C14H12N4O

252.277

TLR8-specific antagonist

DMSO:30 mg/mL (118.92 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years