Pam3CSK4 TFA 是 Toll 样受体 1/2 激动剂，对人 TLR1/2 的EC50为 0.47 ng/mL。

Pam3CSK4 TFA is an agonist of toll-like receptor 1/2 (TLR1/2) (EC50 of 0.47 ng/mL for human TLR1/2).

Pam3CSK4 is a TLR1/2 heterodimer recognises triacylated lipopeptides[1]. Species differences were seen between the responses to Pam2CSK4 and Pam3CSK4 at TLR2/1. Pam3CSK4 (1 μg/mL) enhances the antibacterial functions of granulocyte macrophage-colony stimulating factor (GM-CSF) induced neutrophils to Methicillin-resistant Staphylococcus aureus (MRSA)[2].

112208-01-2

C87H159F9N10O19S

1852.33

Pam3Cys-Ser-(Lys)4 TFA;Pam3CSK4 TFA

H2O:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years