2,4-Diamino-6-hydroxypyrimidine 是GTP cyclohydrolase I(蛋白从头合成中的限速酶) 的选择性抑制剂。它能够抑制NO的产生以及阻断 Tetrahydrobiopterin (BH4) 的合成。

2,4-Diamino-6-hydroxypyrimidine (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis

56-06-4

C4H6N4O

126.119

DAHP;2,4-二氨基-6-羟基嘧啶

DMSO:25 mg/mL (198.22 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years