Acrivastine 是一种短效组胺 1 受体拮抗剂，可用于研究过敏性鼻炎。

Acrivastine is a short-acting histamine 1 receptor antagonist.

Acrivastine (usually 8mg three times daily) is an effective and well-tolerated antihistamine in the treatment of chronic urticaria and allergic rhinitis. Acrivastine causes less drowsiness than clemastine, the incidence of adverse effects being indistinguishable from that with placebo or terfenadine. In the treatment of dermatoses in which histamine has a pathogenetic role, the efficacy of acrivastine is superior to that of placebo and similar to that of usual dosages of clemastine, hydroxyzine, chlorpheniramine, cyproheptadine or terfenadine [1]. Both 4 mg and 8 mg acrivastine alleviate the symptoms of seasonal allergic rhinitis with significant improvements in the symptom scores for sneezing, running nose and the calculated overall score. In addition, 8 mg acrivastine reduces the symptom scores for watery eyes and itchy throat. Acrivastine is both well tolerated and effective in the treatment of seasonal allergic rhinitis [2].

87848-99-5

C22H24N2O2

348.446

Semprex;Acrivastin;BW825C;阿伐斯汀

DMSO:10 mg/mL,warmed&ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years