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Oxytetracycline hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Oxytetracycline hydrochloride图片
CAS NO:2058-46-0
包装与价格:
包装价格(元)
100 mg电议
200 mg电议
500 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
Oxytetracycline HCl
盐酸土霉素
Dalimycin
Oxytetracycline, Sodium Salt
Oxytetracycline.HCl
Biosolvomycin
Dalinmycin
产品介绍
Oxytetracycline hydrochloride 是由 Streptomyces rimosus 生产的,一种具有抗菌活性的四环素衍生物。它干扰氨酰-tRNA 与 mRNA-核糖体复合物的结合,从而阻止肽延伸并抑制蛋白质合成。

产品描述

Oxytetracycline Hydrochloride is a tetracycline derivative produced by Streptomyces rimosus with antimicrobial activity. It interferes with the binding of aminoacyl-tRNA to the mRNA-ribosome complex, resulting in preventing peptide elongation and inhibiting protein synthesis.

体内活性

The 10-day effect of oxytetracycline at therapeutic doses (82.8 mg/kg bw to 1 % bw/day) was species-specific. Oxytetracycline increases the enzymatic activity of CYP3A4 in Ictalurus punctatus, increases the protein expression of CYP3A4 in Oreochromis niloticus, and depletes hepatic CYP3A4 in the latter, and also increases the relative liver weight of Morone chrysops x M. saxatilis [1]. Oxytetracycline is limited to 100 μg/kg in muscle and breast milk, 200 μg/kg in eggs, 300 μg/kg in liver, and 600 μg/kg in kidney[3].

Cas No.

2058-46-0

分子式

C22H25ClN2O9

分子量

496.89

别名

Oxytetracycline HCl;盐酸土霉素;Dalimycin;Oxytetracycline, Sodium Salt;Oxytetracycline.HCl;Biosolvomycin;Dalinmycin

储存和溶解度

DMSO:100 mg/mL (201.25 mM)
H2O:Insoluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years