HBF-0259 是有效的乙型肝炎病毒 表面抗原分泌选择性抑制剂,在 HepG2.2.15 细胞中的EC50为 1.5 μM。
产品描述
HBF-0259 is an inhibitors of hepatitis B virus surface antigen (HBsAg) secretion with an EC50 of 11.3 μM and a CC50 value of >50 μM in HepG2.2.15 cells. HBF-0259 had a EC50 of approximately 1.5 microM in a secondary, HBV-expressing cell line, with a concentration that exhibited 50% cytotoxicity of >50 microM. The equilibrium concentration of HBF-0259 in aqueous solution at physiological pH was 15 to 16 microM; the selective index was thus >9.
Cas No.
957011-15-3
分子式
C16H12Cl2FN5
分子量
364.2
别名
HBF 0259
储存和溶解度
DMSO:98 mg/mL (269.08 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years