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Hernandezine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Hernandezine图片
CAS NO:6681-13-6
包装与价格:
包装价格(元)
1 mg电议
2 mg电议
5 mg电议
10 mg电议

产品介绍
HERnandezine 是 AMPK 激动剂的激动剂,也是癌细胞中 ABCB1 介导的 MDR 的特异性逆转剂。

产品描述

Hernandezine is an activator of AMPK activator and a selective reversing agent for ABCB1-mediated MDR in cancer cells.

体外活性

Hernandezine inhibits LPS-induced TNF-α expression/production in human macrophage cell lines (THP-1 and U93). Hernandezine inhibits the transport function of ABCB1, and enhances drug-induced apoptosis in cancer cells. Hernandezine significantly resensitizes ABCB1-overexpressing cancer cells to multiple chemotherapeutic drugs at nontoxic, nanomolar concentrations[1].

Cas No.

6681-13-6

分子式

C39H44N2O7

分子量

652.78

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years