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(+)-Fluprostenol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(+)-Fluprostenol图片
CAS NO:54276-17-4
包装与价格:
包装价格(元)
1 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
Travoprost acid
曲伏前列素酸
Fluprostenol, (+)-
AL-5848
产品介绍
(+)-FlupROStenol 是前列腺素 F2 α 的类似物,是一种前列腺素 F2α 受体 PTGFR 激动剂,可降低输卵管糖蛋白 1 (OVGP1) 的表达。

产品描述

(+)-Fluprostenol, an analogue of prostaglandin F2 alpha, is a prostaglandin F2α receptor PTGFR agonist and decreases the expression of Oviductal glycoprotein 1 (OVGP1).

体内活性

(+)-Fluprostenol(s.c. to rats on day 18 of pregnancy) increased cervical creep, or softness, by the following day. Doses of (+)-Fluprostenol 100-fold larger were necessary to increase uterine contractions. (+)-Fluprostenol produced falls in serum progesterone concentrations, increases in 20 alpha-dihydroprogesterone concentrations, no changes in oestradiol or relaxin concentrations and a reduction in the ovarian human chorionic gonadotrophin binding capacity in vitro. (+)-Fluprostenol was less potent in inducing cervical softness when administered per vaginam, and a dose which produced softening in pregnant rats was ineffective in ovariectomized steroid-maintained pregnant or pro-oestrous rats[3].

Cas No.

54276-17-4

分子式

C23H29F3O6

分子量

458.47

别名

Travoprost acid;曲伏前列素酸;Fluprostenol, (+)-;AL-5848

储存和溶解度

DMSO:325 mg/mL (708.88 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years