TG6-10-1 是一种 EP2 拮抗剂。

TG6-10-1 is an EP2 antagonist.

Rac Activity Assays: Rac activity is determined from lysates of the MDA-MB-435 and MDA-MB-231 human metastatic cancer cell lines (from ATCC). Cancer cells in culture medium (DMEM, 10% FBS, pH 7.5) are treated with vehicle (0.1% DMSO) or varying concentrations of EHop-016 (0–10 μM) for 24 h. Rac1 activity is determined using the G-LISA Rac1 activation assay kit.

1415716-58-3

C23H23F3N2O4

448.43

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years