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Tankyrase-IN-2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tankyrase-IN-2图片
CAS NO:1588870-36-3
包装与价格:
包装价格(元)
25 mg电议
50 mg电议
100 mg电议

产品介绍

产品描述

Tankyrase-IN-2 is a selective, potent and orally active inhibitor of tankyrase with IC50s of 10, 7, and 710 nM for TNKS1, TNKS2 as well as PARP1, respectively

体外活性

In DLD1 cells, Tankyrase-IN-2 (1-10000 nM; 24 hours) leads to a dose-dependent increase of tankyrase protein abundance (EC50 of 320 nM). This is in the same potency range as the value for axin2 increase with EC50 of 319 nM.

Cas No.

1588870-36-3

分子式

C17H14F2N2O2

分子量

316.3

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years