MRT 10 是一种七跨膜平滑受体 (Smo) 拮抗剂，通过多种 Hedgehog (Hh) 测定，其IC50=0.65 μM。它与Smo 受体结合的位点是 Bodipycyclopamine。它可用于研究癌症。
产品描述
MRT 10 is a smoothened (Smo) receptor antagonist (an IC50 = 0.5 μM in HEK293 cells transiently expressing mouse Smo). It also inhibits bodipy-cyclopamine binding to the murine Smo receptor (an IC50 = 0.5 μM
Cas No.
330829-30-6
分子式
C24H23N3O5S
分子量
465.52
储存和溶解度
DMSO:30mg/mL (64.44mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
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