Dynarrestin 是一种细胞质动力蛋白 1 和 2的氨基噻唑抑制剂。它能够快速的、可逆的抑制动力蛋白 1 驱动的微管在体外滑动和细胞内动力蛋白 1 和 2 依赖性过程，且不影响 ATP 水解和干扰纤毛发生。它可抑制神经元前体和肿瘤细胞的刺猬因子依赖性增殖。

Dynarrestin is a cytoplasmic dynein 1 and 2 aminothiazole inhibitor that reversibly inhibits dynein 1-driven microtubule sliding in vitro and intracellular dynein 1 and 2-dependent processes without affecting ATP hydrolysis and interfering with ciliogenesis .

2222768-84-3

C22H23F2N3O2S

431.5

DMSO:80mg/mL (185.40mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years