Ivachtin 是一种非肽,非竞争性和可逆的Caspase-3抑制剂,IC50为 23 nM。它是其余胱天蛋白酶的适度抑制剂。
产品描述
Ivachtin is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor(IC50 = 23 nM) and is a modest inhibitor of the remaining caspases.
体外活性
Ivachtin has protective effect in a model of staurosporininduced apoptosis in human Jurkat T cells.
Cas No.
745046-84-8
分子式
C20H21N3O7S
分子量
447.46
别名
Caspase-3 Inhibitor VII
储存和溶解度
DMSO:slightly soluble
DMF:2 mg/mL(4.47 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years