3-Phenyltoxoflavin 是一种 HSP90 (Kd = 585 nM) 抑制剂，具有抗癌活性。

3-Phenyltoxoflavin is an inhibitor of HSP90 (Kd = 585 nM) with anti-cancer activity.

3-Phenyltoxoflavin (0.56 nM-100 μM) dose-dependently competes with biotinylated Hsp90 peptide for binding to TPR2A. In BT474 cells, 3-Phenyltoxoflavin (1 nM-100 μM) dose-dependently inhibits cell proliferation with an IC50 of 690 nM[2].

32502-63-9

C13H11N5O2

269.26

ZINC267655;Phenyltoxoflavin

DMSO:6 mg/mL (22.3 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years