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Caroverine hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Caroverine hydrochloride图片
CAS NO:55750-05-5
包装与价格:
包装价格(元)
2 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
Caroverine HCL
产品介绍
Caroverine hydrochloride 是竞争性可逆的NMDA和AMPA谷氨酸受体拮抗剂。它也是抗氧化和钙阻滞剂,具有血管舒张作用,可用于内耳耳鸣的研究。

产品描述

Caroverine HCL is a potent, competitive and reversible antagonist of NMDA and AMPA glutamate receptor. It is also an antioxidant and calcium-blocking agent that exhibits vasorelaxant action, and can be used for the research of inner ear tinnitus.

体内活性

Caroverine (1 μM; pretreated for 10 min) inhibits the pressor response to KCl (80 mM) and noradrenaline (1 μM) in the rat hindquarter preparation. Caroverine markedly suppresses the contraction caused by KCl (40 mM) in the rat isolated aorta[1].Caroverine (1.44 mg/rat; s.c; 1.0 mL/h for 72 h) attenuates impulse noise-induced hearing loss in the rat[2]

Cas No.

55750-05-5

分子式

C22H28ClN3O2

分子量

401.94

别名

Caroverine HCL

储存和溶解度

DMSO:100 mg/mL (248.80 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years