DNQX是喹恶啉衍生物，是一种选择性和强竞争性的非 NMDA 谷氨酸受体拮抗剂，对 AMPA、kainate 和 NMDA 受体的IC50分别为 0.5、2 和 40 μM。

DNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively)

DNQX has been used to specifically target AMPA and kainate receptor responses and thus differentiate from that of NMDA receptors. DNQX does not stimulate a robust long-term potentiation in the hippocampus[1]

2379-57-9

C8H4N4O6

252.14

FG 9041;二硝基喹酮

DMSO:35 mg/mL (138.81 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years