Eltoprazine hydrochloride 是5-HT1A和5-HT1B受体激动剂，也是5-HT2C受体拮抗剂，pEC50分别为9.96、7.19和6.81。

Eltoprazine hydrochloride is a partial agonist at serotonin 5-HT1A, 5-HT1B, and 5-HT2B receptors (Ki value of 40, 52, and 81 nM, respectively).

Eltoprazine hydrochloride exerts a dose-dependent decrease in aggressive behavior in resident-intruder tests with rats (ID50 = 0.24 mg/kg)[1].

98206-09-8

C12H17ClN2O2

256.73

1-(2,3-二氢苯并[B][1,4]二氧杂芑-5-基)哌嗪;DU 28853 hydrochloride

DMSO:31 mg/mL (120.75 mM)
H2O:28 mg/mL (109.06 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years