Neurokinin A 是速激肽家族的一种肽类神经递质,是人体气管道和胃肠道组织中的主要介体,可通过NK-2受体发挥作用。
产品描述
Neurokinin A (NKA), formerly known as Substance K, is a neurologically active peptide translated from the pre-protachykinin gene.
体外活性
Neurokinin A (substance K) is a peptide neurotransmitter of the tachykinin family with potential as a major mediator in human airway and gastrointestinal tissues. Neurokinin A acts via the NK-2 receptor believed to be localized on smooth muscle cells and pharmacologically coupled to a GTP-binding protein. Neurokinin A is a member of a family of peptide neurotransmitters known as tachykinins which are associated with the central and peripheral nervous systems and display a wide tissue distribution. Tachykinins share the COOH-terminal structure Phe-X-Gly-Leu-Met-NH. The best known members of this family are Substance P and Neurokinin A or Substance K[1].
Cas No.
86933-74-6
分子式
C50H80N14O14S
分子量
1133.33
别名
α-Neurokinin;Neuromedin L;Substance K;神经激肽A
储存和溶解度
H2O:60 mg/mL (52.94 mM)
H2O:100 mg/mL (88.24 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years