Dapiprazole hydrochloride 是 α-adrenergic 阻断剂的药物。
产品描述
Dapiprazole Hydrochloride is an alpha-1-adrenergic antagonist that acts by blocking alpha-adrenergic receptors in the smooth muscle of blood vessels (arteries, arterioles and veins), gastrointestinal tract, and radial smooth muscle of the iris.
体内活性
Sixty normal male and female volunteers between 18 and 40 years of age were recruited for a double-masked, placebo-controlled, crossover study in which each eye of each subject was dilated with 2.5% phenylephrine. After one hour, one eye was treated with 0.5% dapiprazole, and the contralateral eye was treated with placebo.
Cas No.
72822-13-0
分子式
C19H28ClN5
分子量
361.92
别名
Glamidolo Hydrochloride;Reversil Hydrochloride;盐酸达哌唑
储存和溶解度
DMSO:31 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years