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Octopamine hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Octopamine hydrochloride图片
CAS NO:770-05-8
包装与价格:
包装价格(元)
500 mg电议
1 g电议

产品名称
章鱼胺盐酸盐
(+,-)-Octopamine HCl
章胺盐酸盐
(±)-p-Octopamine hydrochlorid
产品介绍
OCTopamine hydrochloride 是一种与去甲肾上腺素结构相关的生物单胺类物质,在无脊椎动物中起着神经调节剂、神经激素和神经递质的作用。它对转染人 alpha2-肾上腺素受体(ARs)的中国仓鼠卵巢细胞 α2-ARs 有刺激作用。它提高糖原分解、糖酵解、糖异生、摄氧量和门脉灌注压。

产品描述

Octopamine (OA) is a biogenic monoamine structurally associated with noradrenaline. It can serve as a neurohormone, a neurotransmitter, and a neuromodulator in invertebrates.

体外活性

Octopamine is present in relatively high concentrations in neuronal as well as in non-neuronal tissues of most invertebrate species studied, and modulates almost every physiological process. Octopamine acts as neurohormone including desensitization of sensory inputs, influence on learning and memory, or regulation of the mood of the animal in the central nervous system. Octopamine is the only neuroactive non-peptide transmitter whose physiological role is restricted to invertebrates, and all octopamine receptors belong to the family of G-protein coupled receptors. [1]

体内活性

Octopamine (10 mg/mL) is necessary for the acquisition of sugar memory in Drosophila. [2] Octopamine treatment increases responsiveness to brood pheromone and decreased responsiveness to social inhibition. Octopamine acts as an important source of variation in response thresholds and as a modulator of pheromonal communication in insect societies. [3] Octopamine (10 μM) injected into the mushroom body (MB) calyces or the antennal lobe but not the lateral protocerebral lobe produces a lasting, pairing-specific enhancement of extension of the proboscis. Octopamine (10 μM) injected into the MB calyces results in an additional pairing-specific effect, because it does not lead to an acquisition but a consolidation after conditioning. [4] Octopamine treatment significantly elevates levels of octopamine in the brain and caused a significant dose-dependent increase in the number of new foragers. Octopamine treatment is effective only when given to bees old enough to forage, i.e., older than 4 days of age. Octopamine influences division of labor in honey bee colonies. [5]

Cas No.

770-05-8

分子式

C8H12ClNO2

分子量

189.64

别名

章鱼胺盐酸盐;(+,-)-Octopamine HCl;章胺盐酸盐;(±)-p-Octopamine hydrochlorid

储存和溶解度

DMSO:200.4 mM
H2O:200.4 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years