Flibanserin 一种具有口服活性的 5-HT1A 受体激动剂和 5-HT2A 受体拮抗剂,Ki 值分别为 1 和 49 nM。它与多巴胺 D4 受体结合,Ki值在 4 到 24 nM之间。它是一种血清素能抗抑郁药,用于治疗性欲减退症。
产品描述
Flibanserin is a serotonergic antidepressant used to treat hypoactive sexual desire disorder. Flibanserin has been associated with a low rate of minor serum aminotransferase elevations during treatment but has not been linked to instances of clinically apparent acute liver injury.
Cas No.
167933-07-5
分子式
C20H21F3N4O
分子量
390.41
别名
氟立班丝氨;BIMT-17BS;Girosa;BIMT-17
储存和溶解度
DMSO:45 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years