Baclofen hydrochloride 是一种 GAMMA-AMINOBUTYRIC ACID 衍生物,是一种特异性 GABA-B 受体激动剂。它用于治疗肌肉痉挛,尤其是由于脊髓损伤引起的肌肉痉挛。其治疗效果来自于脊髓和脊髓上部位的作用,通常是减少兴奋性传递。
产品描述
Baclofen hydrochloride is a GAMMA-AMINOBUTYRIC ACID derivative that is a specific GABA-B RECEPTORS agonist. It is used in the treatment of MUSCLE SPASTICITY, especially that due to SPINAL CORD INJURIES. Its therapeutic effects result from actions at spinal and supraspinal sites, generally the reduction of excitatory transmission.
Cas No.
28311-31-1
分子式
C10H12Cl2NO2
分子量
249.11
别名
4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years