[Leu5]-Enkephalin acetate(58822-25-6 free base) 是一种参与伤害感受的内源性神经肽,是 δ-opioid和 μ-opioid受体的激动剂(Kis 分别为 4.0 和 3.4 nM)
产品描述
[Leu5]-Enkephalin acetate is an endogenous neuropeptide involved in nociception and an agonist of δ-opioid and μ-opioid receptors (Kis = 4.0 and 3.4 nM, respectively)
体内活性
[Leu5]-Enkephalin is found in the brain, the brainstem, and the spinal cord as well as in the peripheral nervous system. Leu-Enkephalin (1 mg/kg) decreases the visceromotor response to colon distension in a mouse model of visceral pain induced by colorectal distension[1].
Cas No.
T7173L
分子式
C28H37N5O7
分子量
555.63
别名
亮氨酸脑啡肽;Leu-enkephalin;Leucyl-enkephalin;Leucine enkephalin
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years