Autocamtide-2-related inhibitory peptide 是一种高度特异性和有效的 CaMKII 抑制剂,IC50 为 40 nM。
产品描述
Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.
体外活性
Autocamtide-2-related inhibitory peptide (a novel synthetic peptide ATP) is a potent inhibitor of CaM-kinase II with an IC50 of 40 nM, which is active in the presence or absence of Ca2+/calmodulin. It is 50 and 500 times more potent than CaMK-(281-302Ala286) and KN-93,respectively, under the assay condition used[1].
Cas No.
167114-91-2
分子式
C64H116N22O19
分子量
1497.767
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years