PD 117519 是一种A2A腺苷激动剂,在药理动物模型中有口服降压作用。
产品描述
PD 117519 is an agonist of adenosine receptor
体内活性
PD 117519?selectively binds to adenosine A2 receptors (IC50 = 30 μM) over A1 receptors (IC50 = 810 μM) in rat brain membranes.?PD 117519 increases heart rate and decreases systolic blood pressure in normotensive dogs when administered at doses of 2 or 10 mg/kg[1].
Cas No.
96392-15-3
分子式
C19H21N5O4
分子量
383.408
别名
(R)-N-(2,3-二氢-1H-茚基)腺苷;CI947
储存和溶解度
DMSO:100 mg/mL (260.82 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years