Aurintricarboxylic acid 是高效的αβ-亚甲基-ATP 敏感选择性P2X1Rs和P2X3Rs变构拮抗剂。 它是核糖核酸酶和拓扑异构酶 II 的有效抑制剂,可阻止核酸与酶结合。
产品描述
Aurintricarboxylic acid is a strong inhibitor of topoisomerases and other nucleases. It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme.
体外活性
Aurintricarboxylic acid (ATA) is a known Stp1 inhibitor with an IC50 of 1.03 μM[1].
Cas No.
4431-00-9
分子式
C22H14O9
分子量
422.34
别名
NSC-4056;NSC4056;NSC 4056;金精三羧酸;ATA
储存和溶解度
DMSO:125 mg/mL (295.97 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years