NRC-2694 是表皮生长因子受体的有效拮抗剂,具抗增殖、有抗癌的活性。
产品描述
NRC-2694 is an antagonist of the epidermal growth factor receptor (EGFR). It has anti-cancer and anti-proliferative properties.
体外活性
NRC-2694 (80 ng) induce comparable inhibition of EGFR expression.
体内活性
NRC-2694 (10 mg/kg) regresses the tumor in mice. The maximum tolerated dose of NRC-2694 in male and female mice is 2000 mg/kg (p.o.), in toxicity studies .
Cas No.
936446-61-6
分子式
C24H26N4O3
分子量
418.49
储存和溶解度
DMSO:250 mg/mL (597.39 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years