Osteogenic Growth Peptide (10-14) acetate是一种 Src 抑制剂,是一种有效的有丝分裂原和促成骨和造血因子。Osteogenic Growth Peptide (10-14) acetate负责与 OGP 受体结合并激活细胞内 Gi 蛋白激酶信号通路。
产品描述
Osteogenic Growth Peptide (10-14) acetate is a Src inhibitor and an effective mitogen and stimulator of osteogenesis and hematopoiesis. Osteogenic Growth Peptide (10-14) acetate is responsible for the binding to the OGP receptor and activates an intracell
体外活性
In fibroblast and osteoblast cell lines, Osteogenic Growth Peptide (10-14) acetate induced proliferation and differentiation[2]. Osteogenic Growth Peptide (10-14) acetate induced TPO-primed M07-e cells differentiation through RhoA/TGFβ1/SFKs signalling pathway[3].
体内活性
In mice and rats, Osteogenic Growth Peptide (10-14) acetate increased bone formation and trabecular bone density and stimulated fracture healing[4].
Cas No.
T37603L
分子式
C26H33N5O9
分子量
559.57
别名
Osteogenic Growth Peptide (10-14) acetate(105250-85-9 Free base)
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years