BRD9539 是一种组蛋白甲基转移酶G9a抑制剂，IC50为 6.3 μM，还抑制PRC2活性。

BRD9539 is an inhibitor of euchromatin histone methyltransferase 2 (EHMT2), also known as G9a, with an IC50 value of 6.3 μM

BRD9539 is selective for G9a and PRC2 over SU39H1 and NDMT1 up to a concentration of 40 μM. It is more potent than BRD4770 in enzyme assays but has no activity in cell-based assays when used at concentrations of 5 and 10 μM.

1374601-41-8

C24H21N3O3

399.45

DMSO:35 mg/mL (87.62 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years